International Journal of Pharmaceutical and Health Research <p>coming soon</p> en-US (Dr.N. Sriram) (Dr N. Sriram) Tue, 21 Nov 2023 06:49:53 +0000 OJS 60 Review on Post Market Surveillance of Covid-19 Vaccines in Clinical Trials <p>Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a type of coronavirus that causes the Coronavirus Disease 2019 (COVID-19), which has been the most challenging pandemic in this century. We discussed about the post marketing surveillance of the given vaccines like Pfizer, Sputnik, AstraZeneca, Covaxin and Sinopharm and also that the trials tested two slightly different viral vector vaccines which use genetically engineered adenoviruses to produce corona virus proteins in the body on 76 volunteers. We outline the essential Vaccines antibodies to fight against the COVID-19 in addition we summarize the countries which are denied to use the vaccines. And also the approval of the countries and mainly the covaxin is yet to introduced the vaccines through nasal route is the upcoming vaccination process. And finally we discussed about the public responses of the vaccinations during the pandemic situations.</p> R. Sundhararajan, G. Gopi, M. Madeshwaran, H. Mohamed Faizullah, A. Mohamed Ibrahim, B. Mohamed Niyas Khan, M. Mohamed Safran Copyright (c) 2023 International Journal of Pharmaceutical and Health Research Thu, 21 Dec 2023 00:00:00 +0000 ASTASHINE gummies: A Potential Therapeutic Agent in removing body’s toxins from internal organs and tissues. <p>ASTASHINE gummies contains natural astaxanthin from Haematococcuspluvialis Astaxanthin has exceptional antioxidant activity to combat singlet oxygen when compared to other antioxidants. In particular, Astaxanthin can be used to defend against singlet oxygen damage, which are especially susceptible to aging effects. Results show that the quenching effect of Astaxanthin is 800 times greaterthan coenzyme Q10. Astaxanthin was also about 75 times greater than alpha lipoicacid, about 550 times greater than green tea catechins and about 6000 times greaterthan Vitamin C. The present Article reviews the role of ASTASHINE gummies, A Potential Therapeutic Agent in Liver Health and Disease.</p> C. Rudra Maheshwara Reddy, Govind Shukla, Harish Munnalal Dhoot, C. J Sampath Kumar Copyright (c) 2023 International Journal of Pharmaceutical and Health Research Tue, 05 Dec 2023 00:00:00 +0000 Overview of Silicosis <p>Silicosis/<em>Pneumonoultramicroscopicsilicovolcanoconiosis</em> is a most common <em>pneumo-coniosis</em>. Silicosis is an irreversible fibrotic lung disease which is a form of occupational pulmonary disease caused by the inhalation and deposition of crystalline silicon dioxide (SiO<sub>2</sub>) in the bronchi, lymph node and/or lung Parenchyma as a result of exposure during mining, stone crushing and quarrying activities which occurs mostly in developing countries. Highly populated countries are exposed and the USA, Europe, China and India are listed in the top among the countries. However, the number is still too low because of parallel number of undiagnosed cases. Silicosis induces a series of Inflammatory reactions that further trigger a chronic or acute fibrotic change in the lungs. Silicosis is associated with other comorbidities among&nbsp; which TB,COPD and Cancer are the most prevalent. Till now, there is no curative treatment however some management strategies may help to recover quality of shelf life and slow deterioration.</p> S. Sakthimeena, Ebenezer David, M. Sakthivel, S. Sakthivel, R. Saritha, C. Sasi Kumar Copyright (c) 2023 International Journal of Pharmaceutical and Health Research Tue, 05 Dec 2023 00:00:00 +0000 Flexagold tablets; a blend of natural ingredients provides support for joint health & cartilage regeneration. <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Nutraceuticals are dietary compounds which have a role in the balance of anabolicand catabolic signals in joints. Their regulatory function on homeostasis of cartilage metabolismnutraceuticals is increasingly considered for the management and, above all, the preventionof osteoarthritis (OA). OA is a degenerative disease characterized by cartilage and synoviuminflammation that can cause joint stiffness, swelling, pain, and loss of mobility. It is a multifactorialdisease and, due to the great percentage of people suffering from it and the general increase in lifeexpectancy, OA is considered as one of the most significant causes of disability in the world. OA impairs the structural integrity of articular cartilage that greatly depends on a balance betweenthe anabolic and catabolic processes which occur in chondrocytes and synovial fluid of the joints,therefore the integration with nutraceutical compounds in diet increases the treatment options forpatients with established OA beyond traditional rehabilitation, medications, and surgical strategies.This review summarises the current available scientific literature regarding the effect of FLEXAGOLD Tablets, A Synergistic blend of natural ingredients in supporting joint health.</p> GovindShukla, G. Lohitha, Chandramauli, Balaswamy N.G, Rajkumar, C.J. Sampath Kumar Copyright (c) 2023 International Journal of Pharmaceutical and Health Research Tue, 21 Nov 2023 00:00:00 +0000